Abstract

The action of several amino-hydroxy benzenes and pyrimidines on the survival of air-borne cells has been studied. It has been found that the —OH group is largely responsible for the protectiveness or toxicity of an added compound towards air-borne cells and that the activity of an —OH group can be severely modified by an —NH2 group as well as the ring nucleus on which it is placed. The relative humidity (R.H.) at which the aerosol is held determines the toxicity or protectiveness of a given compound and different chemical configurations in added chemicals appear to be necessary in order to preserve the viability of cells as R.H. is changed.

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