Abstract
Rats were chronically treated with once-daily injections of either haloperidol or vehicle for 21 days. When spontaneous locomotor activity or acquisition of active avoidance in a two-way shuttle box were measured 48 h after the cessation of chronic treatment, the haloperidol-treated animals were significantly more active and performed significantly more avoidance responses. These findings suggest that the increased dopamine receptors that have been reported following chronic haloperidol treatment may have functional relevance.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
