Abstract
A semi-degradable Ti+Mg composite with superior compression and cytotoxicity properties have been successfully fabricated using ink jet 3D printing followed by capillary mediated pressureless infiltration technique targeting orthopaedic implant applications. The composite exhibited low modulus (~5.2GPa) and high ultimate compressive strength (~418MPa) properties matching that of the human cortical bone. Ti+Mg composites with stronger 3D interconnected open-porous Ti networks are possible to be fabricated via 3D printing. Corrosion rate of samples measured through immersion testing using 0.9%NaCl solution at 37°C indicate almost negligible corrosion rate for porous Ti (~1.14μm/year) and <1mm/year for Ti+Mg composites for 5days of immersion, respectively. The composite significantly increased the SAOS-2 osteoblastic bone cell proliferation rate when compared to the 3D printed porous Ti samples and the increase is attributed to the exogenous Mg2+ ions originating from the Ti+Mg samples. The cell viability results indicated absent to mild cytotoxicity. An attempt is made to discuss the key considerations for net-shape fabrication of Ti+Mg implants using ink jet 3D printing followed by infiltration approach.
Published Version
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