Abstract
Abstract Polyetherimide (PEI) microporous membranes with uniform cellular structure, high porosity, and narrow pore size distribution were formed by supercritical CO 2 (ScCO 2 ) phase inversion method, and the membrane was modified to be a matrix for the preparation of affinity membrane due to its low solvent residue and appropriate porous structure. The effects of ScCO 2 temperature and pressure on the morphology and pure water flux of the membrane were investigated. The membrane prepared at 24 MPa and 45 °C with a large mean cell diameter of 6.0 μm, high porosity of 73%, narrow pore size distribution and a pure water flux of 56 L/(m 2 h bar) was coated with chitosan to improve its hydrophilicity and coupled with Cibacron Blue F3GA (CB) as a special ligand to form an affinity membrane (PEI-coated chitosan-CB membrane). The PEI-coated chitosan-CB membrane showed a high adsorption capacity of 33.9 mg/g membrane to bovine serum albumin and was higher than most of affinity membranes. Moreover, the tensile strength of PEI-coated chitosan-CB membrane was 11.58 MPa and was much higher than those of affinity membranes. This work demonstrates that ScCO 2 phase inversion method is a potential method to prepare an affinity matrix.
Published Version
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