Abstract

Soft materials, with their unique physical and chemical properties, provide a platform for simulating and controlling the cellular microenvironment, remarkable progress in their design and fabrication. As soft materials, including amino acids, peptides, proteins, viruses, polysaccharides and macromolecular polymer, which fabricated to the synthetic polymers or hybrid materials are used to fabricated the natural fibers, decellularized matrices and biological tissues also as material source to create scaffolds for tissue engineering. The type, application, and characterization of soft materials, such as medical materials, polymer materials, hydrogels, nature mateirals, nanomaterials, biodegradable biopolymers, electroactive polymers (EAPs), piezoelectric materials and magnetostrictive materials are discussed. Additionally, their applications in cell culture, tissue regeneration, and drug delivery are explored. Understanding and utilizing these fabricated soft materials contribute to advancements in cell biology and tissue engineering, leading to innovative solutions for clinical applications and further development in these fields.

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