Abstract
The insula is a comprised of multiple cortical regions including: dorsal anterior (dAI), ventral anterior (vAI), and posterior (PI), all with distinct connectivity profiles and behavioral functions. Previous studies have shown the insula to be abnormal in schizophrenia. Here we tested the hypothesis that dAI connectivity is related to cognitive impairment, whereas PI and vAI connectivity is related to positive and negative symptoms, respectively, in schizophrenia.
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