Abstract
Spinal cord compression due to extramedullary hematopoiesis is a rare neurosurgical problem that is successfully treated with urgent decompression. Here we report the case of a young man with hemoglobin Lepore disease and beta thalassemia who presented with 1 month of lower extremity weakness and urinary retention. The patient underwent urgent thoracic laminectomies and recovered fully. This pathology can be treated with multiple modalities; however, decompression must remain in the neurosurgeon's armamentarium in the acute setting.
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