Extraintestinal manifestation of Crohn’s disease in an 11-year-old girl: a rare case report with review

Abstract

Crohn’s disease (CD) is an inflammatory condition of the gastrointestinal tract with extraintestinal manifestations. Of all the patients affected by CD 40% experience at least one extraintestinal manifestation of the disease, the skin being the most common site of extraintestinal involvement. We are reporting a case of 11-year-old female child presented to us in the Dermatology OPD with redness and swelling of both upper and lower lip for a duration of 1 year, with swelling of right labia major for 3 months. Skin biopsy showed keratotic plugging, follicular plugging, and loss of rete ridges. Entire dermis and subcutis shows noncaseating granulomas without any giant cells with lymphohistiocytic cuffing around it. The patient was treated with prednisolone followed by methotrexate and supportive measures. There was a decrease in the swelling of face and vulva after a period of 1 month on the treatment. We report this case to draw the attention over the rare cutaneous manifestation of CD.