Extraction, Preparation and Evaluation of Phyllanthus urinaria extract as Antifungal Cream

Abstract

The aim of research work is to formulate an antifungal cream. The cream which is prepared is isolated from natural source. The leaves of Phyllanthus urinaria have active antifungal activity. The genus Phyllanthus is one of the most important groups of plants belonging to the Phyllantaceaceae family. Phyllanthus urinaria is an annual perennial herbal species found in tropical Asia, America, China ad Indian ocean island. P. urinaria is used in folk medicine as a cure to treat jaundice, diabetes, malaria, cancer, bacterial infection, fungal infection. This research gives the therapeutical study for the P. urinaria. The extract is isolated with help of ethanol. The cream is prepared with various pharmaceutical ingredient. Antifungal activity is done with the Aspergillus niger, Candida albicans. This cream is then examined and stability test is performed, physicochemical reactions are done to determine chemical constituents present in the extract.