Extraction, Characterization and Antibacterial Potential Assessment of Polar Phytoconstituents of Caesalpinia bonducella Seeds Extract

Abstract

Plant-based medicine has been utilized to cure ailments at a low cost all over the world, medicinal plants are the primary source of medicines and the healthcare system. Traditional medicine has long utilized the seeds of Caesalpinia bonducella to cure a variety of symptoms and afflictions, including malaria, colic, fever, edema, leprosy, and abdominal pain. The current investigation aimed to identify the polar phytoconstituents and their antibacterial activity in Caesalpinia bonducella seed extracts using polar solvents (methanol, ethanol). The extraction of the phytoconstituents of seed powder of Caesalpinia bonducella was carried out by using Soxhlation method. Then the extract was examined by FT-IR, RP-HPLC, and the traces were confirmed by using the GC-MS technique. Antibacterial studies of the extract showed that the active constituents present in the extract have considerable activities against microbes like Staphylococcus aureus, Escherichia coli, Aspergillus niger, and Salmonella typhi. Perhaps it could serve as a substitute for the commercially available synthetic antibiotics. A microbial assay has been performed to assess the antibacterial potency of the identified phytochemicals.