Extracorporeal shock wave treatment for Peyronie's disease using EDAP LT-02; preliminary results.

Abstract

Abstract Background : Peyronie’s disease is an idiopathic fibrosis of the tunica albuginea of the penis, which often causes erectile dysfunction. No effective therapy except surgery has been available for Peyronie’s disease. We investigated the clinical efficacy of extracorporeal shock wave treatment (ESWT) using EDAP LT‐02 as an alternative method of treatment for Peyronie’s disease. Methods : Five patients aged 35–65 years were treated by ESWT. All patients had undergone unsuccessful medical treatment before ESWT. Each patient was treated by ESWT (7–40 storages at an energy density of 45–96 MPa) between three and five times at 4‐week intervals. Although no patient needed anesthesia, all were administered diclofenac suppository (50 mg) before ESWT. Results : Of the five patients, four were eligible for evaluation. The penile plaque disappeared in one patient (25%). In the other three patients (75%), the penile plaque did not disappear, but softened. Although no improvement of erectile penile curvature was recognized, erectile penile pain disappeared in all patients. Conclusions : These results indicate that ESWT is a possible alternative to surgery in the treatment of Peyronie’s disease.