Abstract
Malaria is one of the tropical diseases which cause high rate of morbidity and mortality. The disease is caused by the infection of protozoan parasites in the genus Plasmodium . The severe syndromes of malaria infection arise from the complex sequences of parasite-host interactions. It starts with parasite invasion and followed by the rupture of infected red blood cells causing the release of parasite products that activate the host immune response. During the past decade, research on the functions of extracellular vesicles (EVs) in many diseases including malaria has increased dramatically. This article reviews the role of EVs in malaria immunopathogenesis. Investigations into modulators in immune response, ubiquitous mechanism for intercellular communication between parasite-parasite and parasite-host, as well as its usefulness as the diagnostic biomarkers are highlighted.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.