Abstract
Extracellular membrane microvesicles and nanotubes in the brain: understanding their nature, their function in cell-to-cell communication, their role in transcellular spreading of pathological agents and their therapeutic potential
Highlights
The present Special Issue encompasses thirteen reviews and original articles which outline recent progresses in understanding the biogenesis, biophysical properties and the possible role of nanotubes and extracellular membrane vesicles (EMVs) in the healthy and diseased brain
The attention turns toward EMVs secreted by neural cells, especially exosomes, their biogenesis and role in inter-neuronal signaling at the synapse, where exosomes may strongly influence plasticity phenomena (Chivet et al, 2012)
Three additional review articles broaden the role of neural EMVs to neuron-glia communication in the central and peripheral nervous system
Summary
The present Special Issue encompasses thirteen reviews and original articles which outline recent progresses in understanding the biogenesis, biophysical properties and the possible role of nanotubes and EMVs in the healthy and diseased brain. The attention turns toward EMVs secreted by neural cells, especially exosomes, their biogenesis and role in inter-neuronal signaling at the synapse, where exosomes may strongly influence plasticity phenomena (Chivet et al, 2012).
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