Abstract

Celiac disease, also known as gluten-sensitive enteropathy, is a chronic disorder of digestive tract mediated by immune mechanisms, resulting in an inability to tolerate gluten and its related proteins in genetically predisposed individuals. Gluten is one protein commonly found in wheat, rye and barley. This disease has a wide spectrum clinical presentations and affects a wide age range on which it has a significant impact in terms of development and morbidity. Therefore, we found it important to study investigation of the variety of extraintestinal manifestations in pediatric celiac patients and identification of possible strategies that can be adapted to diagnose and treat them as soon as possible.

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