Abstract

It has been reported that QM may have antiviral function in invertebrate. However, it has not been seriously investigated whether insect QM plays a critical role in antiviral immunity against nucleopolyhedrosis virus (NPV). In this context, in silico identification and comparative analysis of Spodopetera exigua QM cDNA was conducted. As expected, it is highly conserved protein. To further examine whether entomopathogenic NPV up‐regulates the level of SeQM mRNA, budded virus (AcMNPV‐BV) was infected to the 3rd instar larvae. Real‐time PCR analysis of SeQM in virus‐infected larvae with poly I:C was conducted and potential significance of SeQM was discussed. It remains to elucidate the precise function of SeQM during antiviral immune responses by using RNA interference.

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