Abstract
Objective To explore the expression and significance of haptoglobin(Hp)in papillary thyroid carcinoma. Methods Reverse transcriptase-polymerase chain reaction(RT-PCR) and Western blotting were applied to detect the expression of Hp in 112 cases of papillary thyroid carcinoma,67 cases of benign thyroid node and 50 cases of normal thyroid tissues. Results The relative expression value of Hp mRNA was(0. 913±0. 102)in papillary thyroid carcinoma tissues, which were over-expressed comparing with benign thyroid node(0. 357±0. 009)and normal thyroid tissue(0. 296±0. 008) groups(P 0. 05).In addition,although the level of Hp mRNA increased with the higher clinical stages, there were no statistical significance(P> 0. 05). Conclusion Our results suggested that Hp might play a key role in papillary thyroid carcinoma occurrence.Moreover, findings in the present study also provided evidence for the diagnostic and therapeutic strategies in the treatment of papillary thyroid carcinoma. Key words: Haptoglobin; Papillary thyroid carcinoma
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
