Abstract
Benzofuran serves as the primary active pharmaceutical ingredient (API) in a plethora of both naturally occurring and synthetic drugs known for their potent biological activities. The diverse array of biological effects demonstrated by benzofuran and its analogues encompasses anticancer, anti-microbial, anti-inflammatory, anti-fungal, analgesic, anti-parasitic, anti-hyperglycemic, anti-hyperlipidemic, anti-convulsant, antipyretic, anti-tubercular, anti-Alzheimer, and antioxidant properties, among others. Given this extensive range of therapeutic potentials, benzofuran and its derivatives have garnered significant attention and are extensively utilized in pharmaceutical research and development. This review article focuses specifically on the anti-cancer properties of benzofuran and its derivatives, underscoring the pivotal role of benzofuran as a prominent and versatile scaffold for designing and developing novel therapeutic agents.
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