A multifunctional cucurbit[6]uril-based supramolecular assembly for rifampicin and MnO4− sensing and anti-counterfeiting

Abstract

A unique CB[6]-based fluorescent sensor, CB[6]·NH(CH3)2·DMF·ANS (1) (CB[6] = cucurbit[6]uril, ANS−=5-amino-2-naphthalenesulfonic acid ion) was successfully synthesized under solvothermal condition. 1 can provide highly selective sensing of antibiotic rifampicin (RFP) and MnO4− by fluorescence quenching with a strong quenching constant (KSV = 4.81 × 104 for RFP antibiotic and KSV = 3.13 × 104 for MnO4− ion), low limit of detection (LOD = 0.12 μM for RFP antibiotic and LOD = 0.077 μM for MnO4− ion) and fast response times. Practical application revealed that it was feasible to detect RFP in bovine serum and artificial urine, it can also realize the detection of MnO4− in tap water. Even more exciting to us is that, 1 based fluorescent power and hydrogel were also prepared and used as solid platforms in information encryption and visual detection. This work extends the multifunctional application scope of CB[6]-based supramolecular assembly.