Abstract
A comprehensive discussion of craniofacial evolution, development, and contemporary trends in the discipline are provided in this narrative review. The study begins with an outline of the craniofacial complex's evolutionary history and then covers important discoveries from investigations in comparative anatomy, paleontology, and genetics. It highlights the interaction between hereditary and environmental variables as it explores how molecular pathways and embryonic development shape craniofacial structures. Clinical consequences of cleft lip and palate and other craniofacial anomalies are discussed together with the latest developments in regenerative medicine and surgery. The paper discusses emerging trends that have implications for customized medicine and comprehending human variety. These trends include high-resolution imaging, genetic analysis, and interdisciplinary collaborations. All things considered, this study emphasizes how crucial interdisciplinary methods and technology advancements are to expanding our knowledge of craniofacial biology and pathology.
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