Exploring the Chemical Diversity of Andrographis paniculata: GCMS Characterization of Ethyl Acetate Extracts

Abstract

This research delves into the diverse phytochemical composition of Andrographis paniculata, a renowned medicinal herb with a rich history in traditional use. Employing GC-MS, our objective is to comprehensively identify and characterize phytochemical compounds within ethyl acetate extracts. The study holds significant promise due to the broad spectrum of medicinal applications associated with Andrographis paniculata. The ethyl acetate extracts of the plant were obtained using the cold maceration method, followed by preliminary phytochemical analysis. The findings reveal the presence of steroids, terpenoids, and alkaloids in the ethyl acetate extracts, while tannins, saponins, flavonoids, and cardiac glycosides were notably absent. GC-MS analysis further unveils 29 unique compounds, encompassing alkaloids, terpenoids, and wax. Benzeneethanamine, 2, 5-difluoro-β, 3, 4-trihydroxy-N-methyl, an alkaloid, and 3, 7, 11, 15-tetramethyl-2-hexadecen-1-ol, a prominent terpenoid, stand out among the identified compounds. This research addresses a dearth of phytochemical analysis within the specific locale of Kom-Kom in Oyigbo L.G.A of Rivers, making it a unique contribution to the field. The variations in phytochemical composition attributed to geographic location and extraction solvents underscore the importance of this study