Abstract

In this study, the optimal monochromatic energy level in dual-energy spectral CT required for imaging coronary stents after percutaneous coronary intervention (PCI) was explored. Thirty-five consecutive patients after PCI were examined using the dual-energy spectral CT imaging mode. The original images were reconstructed at 40–140 keV (10-keV interval) monochromatic levels. The in-stent and out-stent CT values at each monochromatic level were measured to calculate the signal-to-noise ratio(SNR) and contrast-to-noise ratio (CNR) for the vessel and the CT value difference between the in-stent and out-stent lumen (dCT (in–out)), which reflects the artificial CT number increase due to the beam hardening effect caused by the stents. The subjective image quality of the stent and in-stent vessel was evaluated by two radiologists using a 5-point scale. With the increase in energy level, the CT value, SNR, CNR, and dCT (in–out) all decreased. At 80 keV, the mean CT value in-stent reached (345.24 ± 93.43) HU and dCT (in–out) started plateauing. In addition, the subjective image quality of the stents and vessels peaked at 80 keV. The 80 keV monochromatic images are optimal for imaging cardiac patients with stents after PCI, balancing the enhancement and SNR and CNR in the vessels while minimizing the beam hardening artifacts caused by the stents.

Highlights

  • In this study, the optimal monochromatic energy level in dual-energy spectral CT required for imaging coronary stents after percutaneous coronary intervention (PCI) was explored

  • A major clinical problem is postoperative stent thrombosis, which can lead to in-stent restenosis (ISR), bringing many risks such as potential recurrent cardiovascular adverse events, seriously affecting the long-term prognosis of p­ atients[4]

  • The massive data of dual-energy spectral CT imaging increase the difficulty of clinical application, this study aimed to screen the optimal monochromatic energy level for the evaluation of coronary stents after PCI to optimize dual-energy spectral imaging of coronary stents

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Summary

Introduction

The optimal monochromatic energy level in dual-energy spectral CT required for imaging coronary stents after percutaneous coronary intervention (PCI) was explored. The in-stent and out-stent CT values at each monochromatic level were measured to calculate the signal-to-noise ratio(SNR) and contrast-to-noise ratio (CNR) for the vessel and the CT value difference between the in-stent and out-stent lumen (dCT (in–out)), which reflects the artificial CT number increase due to the beam hardening effect caused by the stents. The 80 keV monochromatic images are optimal for imaging cardiac patients with stents after PCI, balancing the enhancement and SNR and CNR in the vessels while minimizing the beam hardening artifacts caused by the stents. During a dual energy CT scan, data sets both at high and low energy are acquired These polyenergetic datasets allow for the calculation and reconstruction of virtual monoenergetic images. The massive data of dual-energy spectral CT imaging increase the difficulty of clinical application, this study aimed to screen the optimal monochromatic energy level for the evaluation of coronary stents after PCI to optimize dual-energy spectral imaging of coronary stents

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Results
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