Abstract
Background and Objectives: A high workload is a major challenge to health care workers, especially first- line supporters, like nurse assistants, and this has many negative consequences. This study aimed to identify the factors affecting the workload of nurse assistants in one of Tehran hospitals.
 Methods: The research is descriptive- qualitative using qualitative content analysis, with the participation of 13 nurse assistants selected by purposive sampling. Data were collected through semi- structured interviews and after each interview, the data were loaded and analyzed in MAX QDA software and this process continued until data saturation. Please match the last sentence with the farsi version.
 Results: In the findings of continuous data analysis, a total of 473 codes were found in the factors affecting workload in the process of nurse assistants' work system. Finally, they were classified into five categories of Systems Engineering Initiative for Patient Safety model (person, task, organization, tools, equipment and environment).
 Conclusion: Most factors affecting workload are obtained in the organizational component and the least in the environmental component of the Systems Engineering Initiative for Patient Safety model, which indicates the significant role played by interpersonal relationships in the workplace and hospital rules on the workload of nurse assistants.
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