Abstract
Rice commercial production is seriously threatened by various pathogens. Generally, the susceptibility (S) genes in plants are exploited by phytopathogens to promote infection. Dysfunction of S genes may result in recessively inheritable durable and broad-spectrum disease resistance. In this review, we summarize the latest research on S genes that encode proteins contributing to pathogen infection in rice. The S genes in rice are prospective targets of genome engineering to create resistance germplasms. However, the potential pleiotropic effects resulting from the deletion of S genes limit their application in resistance breeding. The newly developed CRISPR/Cas9-mediated genome editing system offers a promising approach for developing transgene-free rice varieties with durable disease resistance.
Published Version
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