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PDF Availablehttps://doi.org/10.1136/gutjnl-2019-319126
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Cite Journal: Gut |  Publication Date: May 7, 2020 |
 Citations: 57 |  License type: open-access |
Affiliation: Wellcome Centre for Human Genetics, University of Oxford, University Hospital of Zurich, University of Adelaide, South Australian Health and Medical Research Institute, John Radcliffe Hospital, Churchill Hospital, University of Birmingham, Changi General Hospital, Queen's University Belfast
ObjectivePathological Wnt pathway activation is a conserved hallmark of colorectal cancer. Wnt-activating mutations can be divided into: i) ligand-independent (LI) alterations in intracellular signal transduction proteins (Adenomatous polyposis coli, β-catenin),...
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