Abstract
The effects of dietary intake of sugar on serum GOT, GPT, AL-P and LDH activity were examined in 4 young healthy volunteers. The experiment lasted 35 days (usual diets 1; 7 days, experimental diets; 21 days, usual diets 2; 7 days). The composition of the experimental diets was rather high in sugar (low protein low fat), and their serum enzyme activity was measured at intervals.The results obtained were as follows.:Serum GOT activity in all subjects increased on experimental diets and the mean activity was approximately 1.7 times the initial level after 21 days in experimental diets. Changes in serum GPT activity were far larger than changes in serum GOT activity. Serum GPT activity in all subjects increased and the mean was about twofold after 21 days in experimental diets. Serum LDH activity showed no significant changes.It is possible to conclude from the results that serum GOT and GPT activity were affected by high sugar diets.
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