Abstract

Alzheimer's disease (hereafter referred to as AD), which is a neurodegenerative malady, featured basically by memory deficiency and cognitive decrease, has been increasingly linked to immune system dynamics in recent studies. This paper aims to review experimental studies that elucidate the relationship between AD and alterations in immune cell functionality. Recent research has shown progress in this area through experiments, highlighting quantitative and functional shifts in T cells, macrophages, neutrophils, and B cells on the growth of AD. The assay insinuates pro-inflammatory cells rising and a decrease in inflammation-suppressing cells. These findings offer valuable insights for future mechanistic investigations and drug development. However, there remain numerous unexplored aspects in this field, such as specific factors exacerbating AD, drug treatments, and the identification of signaling pathways. Future research may benefit from focusing on uncovering signaling pathways as a key avenue for further exploration and understanding.

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