Abstract
7-aminocephalosporanic acid (7-ACA) is the key intermediate powder to product cephalosporin. The ignition temperature test device (NU-TC1000) for dust cloud was used to test the minimum ignition temperature of 7-ACA dust cloud. When the dispersion mass of 7-ACA dust is 0.8g, the minimum ignition temperature of dust cloud is 496°C. The minimum ignition temperature increases first and then reduces with the increase of dispersion mass. When 7-ACA and acetone are mixed in the ratio of 1g 7-ACA plus 0.75ml acetone and the dispersion mass of mixture sample is 0.6g, the minimum ignition temperature of dust cloud is 400°C. Experimental results show that the minimum ignition temperature of dust cloud decreases markedly by adding acetone into 7-ACA dust. How to set powder has a quite influence on the results.
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