Abstract
MECHANICAL prostheses, especially those of the caged-ball type, have enjoyed wide application in the replacement of diseased or defective heart valves. Despite a measure of immediate success attending the insertion of such devices, the long-term results and the occurrence of late sequelae have been such as to prompt the investigation of techniques for valve replacement employing autologous,<sup>1-3</sup>homologous,<sup>4-6</sup>and heterologous<sup>7-9</sup>tissues. The encouraging clinical experience of Senning in the use of fresh autologous fascia lata for the fashioning of aortic valves<sup>3</sup>indicated study of this material in the repair or replacement of atrioventricular valves. The special challenge associated with management of the tricuspid valve disease<sup>10</sup>and the accessibility afforded to this structure by a simple laboratory method suggested the study herewith reported. <h3>Method</h3> Adult mongrel dogs, 16 to 24 kg (35 to 53 lb) in weight, were anesthetized with thiopental sodium (30 mg/kg) and the
Published Version
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