Experimental justification of the use of electromagnetic radiation of the light range and tissue growth factors in the treatment of the failure of intestinal anastomosis

O.m Klimova ,K.o Bichenko ,Yu.v Ivanova ,A.m Korobov ,M.e Tymchenko

doi:10.26565/2076-0612-2019-26-09

Abstract

The research work reflects the results of an experimental study, the purpose of which was to develop a method of sealing the small intestinal anastomosis under peritonitis. The experiment was performed on 20 white Wistar male rats weighing about 250 grams. The possibilities of using physical (light of a certain wavelength) and biological (tissue growth factors) methods in the prevention and treatment of acute inflammatory reactions and stimulation of reparative processes are shown. It is noted that a promising direction for further research on methods for the prevention of insolvency of small bowel anastomoses is the use of low-intensity electromagnetic radiation in visible spectrum in combination with the application of tissue growth factors.

Highlights

Restoring the continuity of the gastrointestinal tract in abdominal surgery is the most critical stage of any intervention, especially in an urgent situation
The choice of the method of application of intestinal anastomosis in conditions of peritonitis remains an urgent problem, since the frequency of suture failure remains high, which was the reason for the experimental study
The aim of this study is to develop a method for sealing the joints of the small intestine anastomosis in acute experimental peritonitis (AEP)

Summary

Introduction

Restoring the continuity of the gastrointestinal tract in abdominal surgery is the most critical stage of any intervention, especially in an urgent situation. The choice of the method of application of intestinal anastomosis in conditions of peritonitis remains an urgent problem, since the frequency of suture failure remains high, which was the reason for the experimental study. The aim of this study is to develop a method for sealing the joints of the small intestine anastomosis in acute experimental peritonitis (AEP)

Objectives

Methods

Results