Abstract
Polymers can separate into polymer dense and polymer dilute liquid phases in solution while multicomponent lipid membranes can separate into distinct phases within the two-dimensional plane of the membrane. Recent theoretical and simulation work predicts the presence of a polymer rich surface phase when these two phase transitions are coupled by including polymer conjugated lipids in membranes, and that the location of this phase boundary is tuned by both polymer and lipid interactions1. This poster will describe our progress towards validating these predictions experimentally, using mixtures of simple polyelectrolytes or FUS proteins coupled to supported membranes or vesicles.
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