EXPERIMENTAL INFECTIOUS STREPTOCOCCUS ENDOCARDITIS AND ITS ARSENICAL THERAPY (SODIUM CACODYLATE)

Abstract

Definition Etiology Experimental Observations by Others Mortality Reports Specific Therapy Animal Experimentation Production of Endocarditis Methods Results Arsenical Therapy Methods Results Discussion Conclusions DEFINITION Names have been introduced at various times descriptive of the pathologic changes occurring in heart valves following infections. Such names as simple acute benign, infectious, bacterial, chronic, and ulcerative endocarditis and more recently endocarditis lenta and subacute endocarditis have been suggested by clinicians. Litten, 1 in 1900, classified infections of the heart valves into acute, malignant and chronic, by the first two meaning infections causing in patients severe symptoms and death in a short time, by the last one mentioned those less severe and of much longer duration. Litten's classification prompted a lively discussion regarding or malignant endocarditis referred to by the early writers. Simons 2 prefers the term bacterial endocarditis, a designation more accurate than malignant, septic or ulcerative. Libman 3