Abstract
The aim: Substantiation of the expediency of screening for iron deficiency in adolescents of Ukraine, determining the relationship between blood ferritin levels and erythrocyte indices. Materials and methods: The literature data analizys and laboratory examinations of 699 patients in medical records throughout Ukraine in children aged 10-19 who applied for medical care in 2018. Results: According to the obtained data we found that there is no significant difference between the ferritin level (p = 0.728) between groups of urban and rural territory of inhabitance (p = 0.728)/ Total amount of children aged 10-15 years with ferritin below normal 7 ng / ml was 16.3%, of which men 7.7%, women 92.3%. According to European guidelines for the determination of iron deficiency, the number of children with ferritin levels less than 30 ng / ml in this group is 63%, of which men 15.9% and women 84.1%. in a group aged 16 (297 results) the number of male children with ferritin levels less than 22 ng / ml is 12%, and female children with ferritin levels less than 10 ng / ml – 31%. According to WHO recommendations with a rate of 30 ng / ml, the number of people with lower rates was 24% males 69% females. Conclusion: When using the reference values recommended by the WHO for the European region as a criterion for iron deficiency, the percentage of adolescents with iron deficiency increases mainly by 2 times in both the male and female groups.
Highlights
Modern evidence-based medicine is aimed to prevent and to provide early diagnostic of diseases and conditions that can affect the overall health of the nation
We studied the literature data according to the screening of iron deficiency anemia in adolescents in other countries, and analyzed subjective, clinical and laboratory examinations of 699 patients in medical records throughout Ukraine in children aged [10-19] who applied for medical care in 2018
To perform the task of the study, we used the data of 699 medical histories with the results of ferritin analysis throughout Ukraine in children aged [10-19] who applied for medical care in 2018
Summary
Modern evidence-based medicine is aimed to prevent and to provide early diagnostic of diseases and conditions that can affect the overall health of the nation. Standardization systems and clinical routes are being developed to help to avoid inefficient and erroneous interventions,. Anemia is a clinical and hematological syndrome characterized by a decrease in the amount of iron in the serum, bone marrow and depot, which leads to a violation of the synthesis of hemoglobin and erythrocytes. According to the WHO, anemia affects about 25% of the world's population, in Europe about 20% of the population, but this figure varies depending on the socio-economic conditions of the country. The vast majority of the total pool of anemias are iron deficiency, and megaloblastic (B12-deficient and folate-deficient), hemolytic, aplastic and anemia of chronic diseases
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