Abstract

Proton radiotherapy has demonstrated benefits in the treatment of certain cancers. Accurate measurements of the proton stopping powers in body tissues are required in order to fully optimise the delivery of such treaments. The PRaVDA Consortium is developing a novel, fully solid state device to measure these stopping powers. The PRaVDA Range Telescope (RT), uses a stack of 24 CMOS Active Pixel Sensors (APS) to measure the residual proton energy after the patient. We present here the ability of the CMOS sensors to detect changes in the signal sizes as the proton traverses the RT, compare the results with theory, and discuss the implications of these results on the reconstruction of proton tracks.

Highlights

  • An internationally renowned expert in image engineering based at the University of Lincoln has developed new medical imaging technology that could revolutionise cancer treatment

  • The research involves medical physicists at the Institute of Cancer Research and University College London, with clinical trials for prostate cancer radiotherapy being undertaken at The Royal Marsden Hospital

  • The initial development of the technology was funded by previous grants from the Engineering and Physical Sciences Research Council (EPSRC) totalling £8.7 million

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Summary

Introduction

An internationally renowned expert in image engineering based at the University of Lincoln has developed new medical imaging technology that could revolutionise cancer treatment. A consortium, led by Distinguished Professor of Image Engineering Nigel Allinson, created DynAMITe, the world’s largest radiation­tolerant silicon imager – 200 times larger than the processing chips in current PCs and laptops. The images it produces show the impact of radiation on tumours very clearly, as well as assisting detection in the earliest stages of disease progression.

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