Abstract

SummaryHomogenates of gastrocnemius muscles from rats trained by means of a 12-wk long program of treadmill running oxidized d-β-hydroxybutyrate-3-14C 2 to 3 times as rapidly as did homogenates of muscles from sedentary animals. This difference was demonstrated at d-β-hydroxybutyrate concentrations of 0.1 and 0.5 mM. This adaptation may help to explain why the physically trained individual has a greater resistance to ketosis than the untrained, during and after prolonged exercise.

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