Abstract

The importance of parasympathetic excitatory and inhibitory neural control of airway smooth muscles has been demonstrated. It is concluded that excitatory (acetylcholine, ACh) and inhibitory (NO- and VIP-related) neurotransmitters co-exist and are co-released from vagus nerve terminals. The latter transmitters can directly relax airway smooth muscles and, at the same time, inhibit ACh release, playing the role of the braking system against bronchoconstriction.

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