Examining the relationship between inflammation markers and anthropometric values in primary care

Abstract

Abstract Background In recent studies, adipose tissue appears to be associated with inflammation. In this study, it was aimed to determine the relationship between inflammation markers and anthropometric measurement values and blood lipid values for purpose in primary health units. Methods The universe of this study has comprised healthy adults admitted to a community health units' diet clinic in a city of eastern Turkey in the city in 2019. Blood analyzes were done in the family medicine laboratory, those with high leukocyte values were excluded and 274 adults were included in the study. The relationship between blood lipid values, complete blood count, inflammation markers, neutrophil lymphocyte ratio (NLO), platelet lymphocyte ratio (PLO) and lymphocyte monocyte ratio (LMO) and anthropometric measurements of adults were investigated. Spearman correlation test, Kruskal Wallis test, Multiple Linear Regression test were used in the analysis of the data. Results The average age of 274 people participating in the study is 34.07 ± 9.92. According to BMI, no significant difference was found between NLO, PLO and MLO ratios. Significantly weak negative correlation between PLO and skeletal muscle, basal metabolic rate, body fluid amount and lean mass; a negative correlation between HDL and BMI, amount of body fat and amount of internal lubrication were found (p < 0,003). The increase in the amount of skeletal muscle causes a decrease in the level of total cholesterol, while the increase in the amount of internal lubrication causes an increase in the level of total cholesterol. A positive weak correlation was found between NLO and LDL(p < 0,001), a very weak positive correlation between NLO and total cholesterol and a very weak positive correlation between LMO and LDL(p < 0,014). Conclusions It was observed that there was a very weak correlation between anthropometric values and cholesterol levels and inflammation markers, and moderate levels of blood lipid values in healthy individuals. Key messages In primary care, measuring the body composition of healthy people at least once a year appears to be a valuable practice. Exercises that increase skeletal muscle and reduce the amount of internal fat should be recommended to patients with high cholesterol or healthy people at risk.