Abstract
Nonmyeloablative allogeneic hematopoietic cell transplantation (HCT) consisting of 2 Gray (Gy) total body irradiation (TBI), dog leukocyte antigen-identical marrow, and short-term postgrafting immunosuppression with cyclosporine and mycophenolate mofetil was developed in the dog model as an effective way to establish long-term, stable mixed hematopoietic chimerism. We hypothesized that Treg cells are crucial to maintaining stable mixed chimerism. All dogs in the current study were stable mixed chimeras established as described.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
