Abstract
The biology of sponges provides clues about how early animals may have dealt with low levels of oxygen.
Highlights
Related research article Mills DB, Francis WR, Vargas S, Larsen M, Elemans CPH, Canfield DE, Worheide G. 2018
Speaking, life with oxygen is better than life without: a given amount of glucose processed in the presence of oxygen produces 18 times as much energy as the same amount of glucose processed without oxygen
The use of oxygen poses risks, and fluctuations in oxygen levels can lead to some of the toxic byproducts of metabolism accumulating in cells
Summary
Related research article Mills DB, Francis WR, Vargas S, Larsen M, Elemans CPH, Canfield DE, Worheide G. 2018. Animals have evolved elegant mechanisms to monitor oxygen levels and respond to changes. When oxygen levels are low, HIF remains intact and activates genes involved in anaerobic metabolism or processes that support oxygen delivery.
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