Abstract
A new approach for hair treatment through coating with nanotubes loaded with drugs or dyes for coloring is suggested. This coating is produced by nanotube self-assembly, resulting in stable 2–3 µm thick layers. For medical treatment such formulations allow for sustained long-lasting drug delivery directly on the hair surface, also enhanced in the cuticle openings. For coloring, this process allows avoiding a direct hair contact with dye encased inside the clay nanotubes and provides a possibility to load water insoluble dyes from an organic solvent, store the formulation for a long time in dried form, and then apply to hair as an aqueous nanotube suspension. The described technique works with human and other mammal hairs and halloysite nanoclay coating is resilient against multiple shampoo washing. The most promising, halloysite tubule clay, is a biocompatible natural material which may be loaded with basic red, blue, and yellow dyes for optimized hair color, and also with drugs (e.g., antilice care-permethrin) to enhance the treatment efficiency with sustained release. This functionalized nanotube coating may have applications in human medical and beauty formulations, as well as veterinary applications.
Highlights
Beauty is inherent to human wellbeing and hair has aesthetic, historic, and cultural significance, and is an indicator of health
Each hair is a skin appendage that consists of a root embedded in the dermis and a hair shaft, a flexible strand composed of hard keratin fibers bound through strong and weak bonds
The results suggest the favored b2i.o2c.iCdearebffonecNt oanf opteurbmesethrin by its halloysite loading, perhaps due to nanotube intestinal penetration, leadinCgatrobopnermmaettehrriianlsu, pptaarktiecuenlahralyncgermapehnet,naen-bdaascehdieovniensg, haawvoeramlsodesahtohwtonllporfo8m5i%se[f2o3r].hair dyeing
Summary
Beauty is inherent to human wellbeing and hair has aesthetic, historic, and cultural significance, and is an indicator of health. Graphene oxide hair formulations were mixed with chitosan, giving brown to Nanomaterials 2019, 9, 903 black colors They demonstrated a durable effect, resisting multiple shampooing, antistatic, and heat dissiNpaantoimoanter[ia1ls92]0.19F, u9,lxleFrOeRnPeEEnRaRnEoVpIEaWrticles have been explored for hair growth stimul3atoifo1n3 [20]. The results suggest the favored biocide effect of permethrin by its halloysite loading, perhaps due to nanotube intestinal penetration, leading to permethrin uptake enhancement, and achieving a worm death toll of 85% [23] Another important issue regarding hair maintenance is hair loss treatments [41]. This demonstrated a toxic-free procedure for dyeing light-colored hair with dark shades, ranging from brown to black These formulations exhibited a resistance to multiple shampoos and antistatic and heat dissipation capabilities [19]. This way, evidence shows that a carbon nano-fibrous shape is important for the development of lung pathogenicity, including inflammation, fibrosis, and granuloma formations [59]
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