Abstract
Over the last 20 years, Evidence-based Medicine has been adapted to create Evidence-based Toxicology (EBT). A milestone was a community-forming conference in Como, Italy, in 2007. Since 2011, the EBT Collaboration is developing and disseminating these concepts. The expanding toolbox of systematic reviews, evidence maps, quality scoring, risk-of-bias analyses, meta-analyses, etc., is increasingly applied in already several thousand systematic reviews in environmental health. More and more, agencies such as the US Environmental Protection Agency, the US Food and Drug Administration and the European Food Safety Authority are leveraging these tools. A particular challenge is the integration of different study types (evidence streams).
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