Abstract

1. The concentrations of γ-amino butyric acid (GABA), glutamic acid and/or ecdysteroids were selectively determined in hemolymph and/or moulting fluid of the Cecropia silkworm, Hyalophora cecropia, the tobacco hornworm, Manduca sexta and the Monarch butterfly, Danaus plexippus, during larval-larval, larval-pupal, diapause pupal and/or pupal-adult development. 2. Titers of GABA and glutamic acid ranged from undetected to 3.3 × 10 −4 and 7.5 × 10 −3 M, respectively. 3. Stage specific GABA titer profiles for the various species possess many common features. 4. In agreement with earlier studies in this laboratory, the appearance of GABA in hemolymph is linked to observed or putative periods of neurosecretory activity.

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