Abstract

AbstractUniProtKB provides the scientific community with a comprehensive collection of protein sequence records containing extensive curated information including functional and sequence annotation. This information is derived from a variety of sources such as scientific literature and sequence analysis programs as well as data imported from automatic annotation systems and external databases. To allow users to ascertain the origin of each data item in a UniProtKB record, an evidence attribution system is being introduced which links each piece of information to its original source. This system allows users to trace the origin of all information, to differentiate easily between experimental and computational data, and to assess data reliability. The current system and plans for its future development and enhancement will be presented.

Highlights

  • UniProtKB data comes from a variety of sources including scientific literature, sequence analysis tools, automatic annotation systems and other databases

  • Links each piece of information in a UniProtKB entry to its original source Differentiates between information added during the manual curation process, imported from other databases or added by automatic annotation procedures

  • Information predicted by automatic annotation systems is linked to the underlying rules which provide the annotation

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Summary

Introduction

UniProtKB data comes from a variety of sources including scientific literature, sequence analysis tools, automatic annotation systems and other databases. Comprehensive collection of protein sequence records containing extensive curated information. Consists of 2 sections, UniProtKB/Swiss-Prot and UniProtKB/TrEMBL.

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