Evaluation to Treatment Adherence, Rational Drug Use in Hemodialysis Patients and Predictive Factors on Dialysis Adequacy

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Objective: This study aimed to evaluate treatment adherence and rational drug use in hemodialysis patients and investigate predictive factors on dialysis adequacy. Materıals and Methods: This is a cross-sectional descriptive study. The data were obtained by examining face-to-face questionnaires and patient files. The Hospitalized Patient Questionnaire and the End Stage Kidney Disease Compliance Questionnaire (ESRD-AQ) were administered to the patients. Kt/V was used for dialysis proficiency. By examining the obtained data, the variables that can be associated with the Kt/V value were investigated. Results: A total of 145 patients were included in the study. Sixty nine percent of the participants were over 51 years of age and 54.5% were male. Median Kt/V level was 1.38 (Q1=1.25; Q3=1.54). As for the medications, those with Kt∕V≥1.2 were found to be using more antihypertensive agents, folic acid, vitamin B12, and vitamin C but less levocarnitine concerning the group with Kt/V<1.2 (p<0.05). The Median Score on the End-Stage Renal Failure Adherence Questionnaire was 1150 (Q1=1050; Q3=1200). Total Adherence Score was found to be statistically significantly higher in the group with Kt/V≥1.2 (p<0.05). Conclusıon: It was determined that the level of treatment adherence of the patients participating in the study were considerably high. The probability of receiving adequate dialysis increased as total adherence scores increased. The knowledge level of patients on rational drug use affects adherence. In this study, folic acid, vitamin C, and levocarnitine were associated with dialysis adequacy.