Abstract

The current study proceeded on six female rabbits weighing 1600 Âą 200 g were used to determine the efficacy of 2% lidocaine (most commonly used concentration) in healing of skin wound. After anesthetized a two full thickness surgical incision were made on two sides of midline in back region of all animals, and divided into two groups randomly .In treated group, the right side were infiltrated with 3 ml of 2% lidocaine ; In control group, the left side were infiltrated with 3ml of normal saline. Sites of intervention were estimated by histopathology. This study evidence 2% lidocaine that delay wound healing process and decrease wound strength ,formation of blood vessel and other skin content as hair follicle and there muscle.

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