Abstract
Mold identification using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) remains uncommon in clinical laboratories. Contributing concerns include limited genus/species spectra in the MALDI-TOF MS libraries, varying success rates in the literature regarding extraction methods and instrumentation, and the lack of practical performance evaluations using early mold colony growth, which would be used in a clinical mycology laboratory. This study used multiple approaches to improve our understanding of the clinical utility and performance of MALDI-TOF MS mold identification.
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