Evaluation of the Therapeutic Efficacy of Alcoholic Extract of Tannins (Before and After Acidosis) on Laboratory Mice Experimentally Infected with the Parasite Cryptosporidium parvum

Abstract

Plants extracts are the one of the most important sources that have been used in both ancient and recent to many facture variants, types of medical drugs and that was the aim of the current study to find safe, effective and available natural alternatives by measuring the therapeutic effect of the alcoholic extract of tannins before and after the acid hydrolysis of the extract, in laboratory mice experimentally infected with C. parvum and using three therapeutic concentrations (2, 1.3, 1) mg / ml, and the alcoholic extract before the acid hydrolysis proved its therapeutic efficacy with a noticeable decrease in the number of Oocyst excreted with the feces, as the Oocyst were no longer excreted from the ninth day of the treatment. Parasite Oocyst on the fifth day of treatment were treated by oral administration of the extract in infected mice, in the other hand the current study recorded that Cryptosporidiais as a common disease in the study area, with infection rate of 26%.