Therapeutic Comparison Between Alcoholic and Aqueous Plant Extract of Tannins with Metronidazole in Experimentally Infected Laboratory Mice Cryptosporidium parvum Oocysts

Abstract

The current study was conducted during the period between from the beginning of October 2021 until the end of March 2022. The aim of the study was to measure the therapeutic efficacy of alcoholic and aqueous extracts from the local tannins Cupressus sempervirens for the treatment of experimental infected laboratory mice with Cryptosporidiosis.
 Through a significant decrease in the number of Oocyst of the parasite that causes infection Cryptosporidium parvum after oral administration of the aqueous and alcoholic extracts with three concentrations (2, 1.3, 1) mg/ml compared to MTZ drug, as the alcoholic extract proved its efficacy by stopping the shedding of parasite Oocyst at the ninth day of treatment with its total absence on the eleventh day of treatment, while the shedding of parasite Oocysts in the group treated with aqueous extract stopped on the eleventh day and completely absent on the thirteenth day of infection.