Evaluation of the optical quality of young patients with myopia using the Double-pass Optical Quality Analysis System

Abstract

Objective To evaluate the optical quality of young patients with myopia by using the Double-pass Optical Quality Analysis System (OQASTM II) to establish a new range of reference values; to further provide evidence for the clinical diagnosis and evaluation of myopia in young patients. Methods This was a cross-sectional study. Three hundred forty-two young patients participated in this study. Patients were divided into three groups based on spherical equivalent (SE) : a low myopia group, a moderate myopia group, and a high myopia group. Optical quality measurements for a 4.0 mm pupil were performed using the OQASTM II. The following parameters were analyzed: the objective scatter index (OSI) , the modulation transfer function cutoff frequency (MTF cutoff) , the Strehl ratio (SR) , visual acuity (VA) at 100%, 20%, and 9% contrasts and the amplitude of accommodation (AMP) . Data were analyzed using ANOVA and pearson correlation. Results ①The normal limits of OSI, MTF cutoff, SR, VA100%, VA20%, VA9%, AMP were 0.48-0.68, 36.54-40.20, 0.22-0.25, 1.22-1.34, 1.25-1.41, 1.32-1.49, 1.18-1.47 in low myopia group, respectively; 0.61-0.76, 34.55-37.07, 0.21-0.22, 1.15-1.24, 1.16-1.26, 1.20-1.30, 1.28-1.48 in moderate myopia, respectively; 1.39-2.20, 28.40-31.99, 0.17-0.19, 0.95-1.07, 0.92-1.05, 0.92-1.05, 1.62-1.88 in high myopia, respectively. As the parameter values increase, visual quality decreases in myopia, while the OSI and AMP values increase. ②The OSI was negatively correlated with the MTF cutoff and SR values and the differences were statistically significant (r=-0.65, -0.50, P 0.05) . Conclusion This study revealed the normal range of reference values of OQASTM II for patients with different refractive statuses. This could provide evidence for establishing reference values, evaluating the visual quality of patients who have different degrees of myopia and discriminating healthy eyes from eyes that have early abnormalities. Key words: Myopia; Visual quality; Optical quality analysis system; Double-pass