Abstract

Abstract The reliability of the Griess nitrite test in the recognition of urinary tract infection has been evaluated, employing several micro-organisms known to reduce nitrate. Although the Griess reaction is able to detect 0.1 μg of sodium nitrite per milliliter, it appears to be of limited value as a screening or diagnostic test for the presence of urinary infection. The inability of some pathogenic bacteria to reduce nitrate, the variable rate of the reaction with other organisms, and the relatively large numbers of microorganisms required to produce detectable nitrite detract from the value of this test as a practical clinical procedure.

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