Epidemiological characteristics and distribution of pathogenic microorganisms in 197 children with urinary tract infection

Abstract

Objective To investigate the epidemiological characteristics, distribution of pathogenic microorganisms and antibiotic susceptibility of children with urinary tract infection, and to provide basis for using antibacterial drugs in clinical. Methods One hundred and ninety-seven children with urinary tract infection hospitalized in Shanxi Provincial Children Hospital from January 2016 to January 2018 were selected as research objects. Then the relative clinical data of all allocated children were retrospectively analyzed. Results The proportion of male and female with urinary tract infections were 62.95% and 37.05%, respectively; patients more than 1 year-old accounted for 53.81% and patients less than 1 year-old accounted for 46.19%; and 31.98% patients were complicated by urinary tract deformity. According to the composition ratio of pathogenic bacteria, Gram-negative bacillus accounted 83.33% (62.18% for Escherichia coli) and Gram-positive coccus accounted 14.74% (both Enterococcus faecium and Enterococcus faecalis were 5.77%). Drug sensitivity analysis showed that Escherichia coli and Klebsiella pneumoniae were sensitive to imipenem, and the sensitivity rate was 98.97% and 100%, respectively. Enterococcus faecium and Enterococcus faecalis were sensitive to vancomycin, linezolid and teicoplanin and sensitivity rates all were 100%. Conclusions The main pathogenic microorganism that causes urinary tract infection in children is Escherichia coli. Drug sensitivity test is very essential for the selection of drugs for patients with urinary tract infection. The clinical applications of medicine should be in line with susceptibility guidance. Key words: Child urinary tract infection; Epidemiology; Distribution of pathogenic microorganisms; Drug sensitivity analysis